Description

Ethyl 2-Oxo-2-(4-Oxotetrahydro-2H-Pyran-3-Yl)Acetate is a high-purity, versatile organic intermediate featuring a functionalized pyranone core. This compound is valued for its role as a key building block in the synthesis of complex heterocyclic molecules and active pharmaceutical ingredients (APIs). It is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel compounds with specific biological activities.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its reactive carbonyl and ester functionalities.
• Fine Chemical Production: Acts as a versatile scaffold for constructing complex heterocycles like fused pyranones and pyrans, which are valuable in material science and specialty chemistry.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploring new chemical spaces in medicinal chemistry.
• Chemical Biology Probes: Useful in the design and synthesis of molecular probes for studying biological pathways and protein-ligand interactions.

Basic Information

Product Name	Ethyl 2-Oxo-2-(4-Oxotetrahydro-2H-Pyran-3-Yl)Acetate
CAS No.	857177-01-6
Molecular Formula	C9H12O5
Molecular Weight	200.19 g/mol
Synonyms	Ethyl (4-oxotetrahydro-2H-pyran-3-yl)oxoacetate; 3-(Ethoxyoxalyl)-4H-pyran-4-one; 4-Oxo-tetrahydro-pyran-3-carboxylic acid ethyl ester oxo derivative; Ethyl 2-(4-oxo-3,4-dihydro-2H-pyran-3-yl)-2-oxoacetate; 3-(Ethoxycarbonylformyl)-4-pyranone; 4-Oxo-3,4-dihydro-2H-pyran-3-carboxylic acid, 2-oxo-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Oxo-2-(4-Oxotetrahydro-2H-Pyran-3-Yl)Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive (hygroscopic); ensure containers are sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.