Description

2-Propanone, 1,1,1-Trichloro-3-Hydroxy- is a specialized halogenated hydroxy ketone compound, identified by CAS NO 856981-81-2. This chemical serves as a valuable synthetic intermediate, prized for its unique molecular structure that enables the introduction of both trichloromethyl and hydroxyl functionalities in a single step. It is primarily required by R&D chemists and process development teams in the pharmaceutical and agrochemical sectors for constructing complex molecules and active ingredients. Our supply ensures high purity and batch-to-batch consistency critical for advanced organic synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring trichloromethyl or specific hydroxy ketone motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where its halogenated structure contributes to biological activity.
• Organic Synthesis Reagent: A versatile reagent in academic and industrial laboratories for constructing complex organic frameworks, including heterocycles and natural product analogs.
• Material Science Research: Investigated as a monomer or cross-linking agent precursor for the development of specialty polymers with unique properties.
• Chemical Intermediate for Fine Chemicals: Employed in the multi-step synthesis of dyes, pigments, and other high-value fine chemicals.

Basic Information

Product Name	2-Propanone, 1,1,1-Trichloro-3-Hydroxy-
CAS No.	856981-81-2
Molecular Formula	C3H3Cl3O2
Molecular Weight	177.41 g/mol
Synonyms	1,1,1-Trichloro-3-hydroxy-2-propanone; 3-Hydroxy-1,1,1-trichloroacetone; 1,1,1-Trichloro-3-hydroxyacetone; Trichlorohydroxyacetone; 3-Hydroxy-1,1,1-trichloropropan-2-one; α,α,α-Trichloro-β-hydroxyacetone; β-Hydroxy-α,α,α-trichloroacetone
EINECS	Contact for details

Quality Control

Our 2-Propanone, 1,1,1-Trichloro-3-Hydroxy- is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the presence of multiple functional groups, it should be stored separately from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.