Description

2-Mercaptopyrimidine-5-Carbaldehyde is a versatile heterocyclic building block featuring both a reactive aldehyde and a thiol group. This compound matters for its critical role as a key intermediate in the synthesis of complex pharmaceutical molecules and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Chelator Development: Serves as a starting material for creating novel ligands in coordination chemistry and metal chelators.
• Material Science Research: Employed in the development of organic semiconductors, conductive polymers, and other functional organic materials.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme activity and protein interactions.
• Cross-coupling Reactions: Acts as a substrate in various palladium-catalyzed cross-coupling reactions to form complex biaryl structures.

Basic Information

Product Name	2-Mercaptopyrimidine-5-Carbaldehyde
CAS No.	856596-02-6
Molecular Formula	C5H4N2OS
Molecular Weight	140.16 g/mol
Synonyms	5-Formyl-2-pyrimidinethiol; 2-Pyrimidinethiol-5-carboxaldehyde; 2-Mercapto-5-formylpyrimidine; 5-Aldehydo-2-mercaptopyrimidine; 2-Thiopyrimidine-5-carbaldehyde; 5-Carbaldehyde-2-mercaptopyrimidine; 2-Sulfanylpyrimidine-5-carbaldehyde
EINECS	Contact for details

Quality Control

Our 2-Mercaptopyrimidine-5-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.