Description

(S)-2-Methyl-n-(Pyridin-3-Ylmethylene)Propane-2-Sulfinamide CAS NO 854497-49-7 is a high-purity chiral sulfinamide compound, widely recognized as a versatile and critical chiral auxiliary in asymmetric synthesis. Its primary value lies in enabling the stereoselective construction of complex molecules, ensuring high enantiomeric purity in final products. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Chiral Auxiliary in Asymmetric Synthesis: Key reagent for inducing chirality in the synthesis of enantiomerically pure compounds.
• Pharmaceutical Intermediate: Used in the research and production of novel drug candidates, particularly for creating stereogenic centers.
• Agrochemical Synthesis: Employed in the development of enantiomerically pure pesticides and herbicides.
• Academic & Industrial R&D: A fundamental building block in medicinal chemistry and process chemistry laboratories for method development.
• Ligand Precursor: Can serve as a precursor for chiral ligands used in catalytic asymmetric reactions.
• Fine Chemical Production: Integral in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	(S)-2-Methyl-n-(Pyridin-3-Ylmethylene)Propane-2-Sulfinamide
CAS No.	854497-49-7
Molecular Formula	C10H14N2OS
Molecular Weight	210.30 g/mol
Synonyms	(S)-2-Methyl-N-(pyridin-3-ylmethylene)propane-2-sulfinamide; (S)-N-(Pyridin-3-ylmethylene)-2-methylpropane-2-sulfinamide; (S)-tert-Butanesulfinamide pyridine-3-carbaldehyde imine; (S)-N-(3-Pyridylmethylene)-2-methyl-2-propanesulfinamide; (S)-2-Methyl-2-propanesulfinamide N-(3-pyridinylmethylene); Chiral Sulfinamide Auxiliary; tert-Butanesulfinimine of 3-Pyridinecarboxaldehyde (S)-form
EINECS	Contact for details

Quality Control

Our (S)-2-Methyl-n-(Pyridin-3-Ylmethylene)Propane-2-Sulfinamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive Certificates of Analysis (COA) for each batch, detailing key parameters such as assay, enantiomeric excess, and impurity profiles. Our quality systems are designed to meet the rigorous standards required for pharmaceutical R&D and advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.