Description

(S)-n-(3,4-Dimethoxybenzylidene)-2-Methylpropane-2-Sulfinamide is a high-purity chiral sulfinamide derivative, widely recognized as a versatile and critical chiral auxiliary in asymmetric synthesis. Its primary value lies in enabling the stereoselective construction of complex molecules, offering researchers and manufacturers precise control over the three-dimensional architecture of target compounds. This compound is essential for pharmaceutical R&D, agrochemical synthesis, and advanced material science, where the introduction of specific stereocenters is paramount for biological activity and material properties.

Application

• Chiral Auxiliary in Asymmetric Synthesis: Employed for the stereoselective formation of carbon-nitrogen and carbon-carbon bonds, crucial for building chiral amines and other nitrogen-containing compounds.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological disorders, cardiovascular diseases, and oncology.
• Agrochemical Synthesis: Applied in the creation of enantiomerically pure herbicides, fungicides, and pesticides, where specific stereochemistry can enhance efficacy and reduce environmental impact.
• Catalyst and Ligand Precursor: Serves as a building block for synthesizing novel chiral catalysts and ligands used in transition metal-catalyzed reactions.
• Academic and Process Chemistry Research: A valuable tool in methodological development for new asymmetric transformations and scale-up process optimization.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.

Basic Information

Product Name	(S)-n-(3,4-Dimethoxybenzylidene)-2-Methylpropane-2-Sulfinamide
CAS No.	854497-40-8
Molecular Formula	C₁₃H₁₉NO₃S
Molecular Weight	269.36 g/mol
Synonyms	(S)-(-)-N-(3,4-Dimethoxybenzylidene)-2-methylpropane-2-sulfinamide; (S)-N-(3,4-Dimethoxybenzylidene)-tert-butanesulfinamide; (S)-tert-Butanesulfinamide, N-[(3,4-dimethoxyphenyl)methylene]-; (S)-N-(3,4-Dimethoxybenzylidene)-2-methyl-2-propanesulfinamide; (S)-N-(3,4-Dimethoxybenzylidene)-t-butylsulfinamide; (S)-N-(3,4-Dimethoxybenzylidene)-2-methylpropane-2-sulfinamide; (S)-N-(3,4-Dimethoxybenzylidene)-2-methyl-2-propanesulfinamide; (S)-N-(3,4-Dimethoxybenzylidene)-tert-butylsulfinamide
EINECS	Contact for details

Quality Control

Our production of (S)-n-(3,4-Dimethoxybenzylidene)-2-Methylpropane-2-Sulfinamide adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. All material is characterized and released against comprehensive specifications, including chiral purity (enantiomeric excess) and chemical assay. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as identity (IR, NMR), purity (HPLC), and specific tests for residual solvents and moisture content.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation and moisture absorption. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.