Description

4-Chloro-4'-Iododiphenyl Ether 99% is a high-purity diaryl ether derivative, a versatile halogenated aromatic building block essential for advanced organic synthesis. Its distinct molecular structure, featuring both chloro and iodo substituents on separate phenyl rings, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for applications such as ligand synthesis, cross-coupling reactions, and the development of functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a rigid, halogenated biphenyl-like scaffold.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the iodine atom offers a handle for further functionalization.
• Material Science & Organic Electronics: Acts as a monomer or building block for creating conjugated polymers, liquid crystals, and organic light-emitting diodes (OLEDs) due to its electron-rich aromatic system.
• Cross-Coupling Reactions: The iodine substituent is an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings, enabling efficient carbon-carbon bond formation.
• Ligand & Catalyst Development: Utilized to synthesize sophisticated chelating ligands for transition metal catalysts used in asymmetric synthesis and industrial processes.
• Chemical Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Item	Details
Product Name	4-Chloro-4'-Iododiphenyl Ether 99%
CAS No.	854257-01-5
Molecular Formula	C₁₂H₈ClIO
Molecular Weight	330.55 g/mol
Synonyms	1-Chloro-4-(4-iodophenoxy)benzene; 4-Chloro-4'-iododiphenyl ether; 4-(4-Chlorophenoxy)iodobenzene; p-Chloro-p'-iododiphenyl ether; 1-Iodo-4-(4-chlorophenoxy)benzene; (4-Chlorophenoxy)-4-iodobenzene; 4-Iodophenyl 4-chlorophenyl ether
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-4'-Iododiphenyl Ether is produced and tested under a strict quality management system to ensure consistent purity and performance. Our standard 99% grade is verified using advanced analytical techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.