Description

5-(4-Fluorophenyl)Thiophene-2-Carboxylic Acid Hydrazide is a high-purity organic building block featuring a thiophene core linked to a fluorinated phenyl ring and a reactive hydrazide functional group. This compound is valued for its role as a versatile intermediate in the synthesis of complex heterocyclic molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active ingredients and functional materials. The CAS number for this compound is 852296-85-6.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Serves as a monomer or functionalizing agent in the creation of conductive polymers, organic semiconductors, and advanced polymeric materials.
• Chemical Synthesis: Employed in organic synthesis to construct complex heterocyclic scaffolds, such as thienopyridines and fused ring systems, via cyclization and condensation reactions.
• Bioconjugation & Probe Development: The reactive hydrazide group allows for conjugation with aldehydes and ketones, useful in creating biochemical probes and labeled compounds.

Basic Information

Product Name	5-(4-Fluorophenyl)Thiophene-2-Carboxylic Acid Hydrazide
CAS No.	852296-85-6
Molecular Formula	C11H9FN2OS
Molecular Weight	236.27 g/mol
Synonyms	5-(4-Fluorophenyl)-2-thiophenecarboxylic acid hydrazide; 5-(p-Fluorophenyl)thiophene-2-carbohydrazide; 2-Thiophenecarboxylic acid, 5-(4-fluorophenyl)-, hydrazide; 852296-85-6; 5-(4-Fluorophenyl)-2-thiophenecarbohydrazide; 5-(4-Fluorophenyl)thiophene-2-carboxylic hydrazide
EINECS	Contact for details

Quality Control

Our 5-(4-Fluorophenyl)Thiophene-2-Carboxylic Acid Hydrazide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.