Description

n-[(1R,2R)-2-Amino-1,2-Diphenylethyl]-2,4,6-Tris(1-Methylethyl)-Benzenesulfonamide is a high-purity, chiral sulfonamide derivative designed for advanced chemical synthesis. This compound serves as a critical chiral ligand or catalyst precursor in asymmetric transformations, enabling the production of enantiomerically pure intermediates. It is essential for research and development laboratories and production facilities in the pharmaceutical, agrochemical, and fine chemical industries seeking to control stereochemistry with high selectivity.

Application

• Asymmetric Catalysis: As a chiral ligand or precursor for transition metal catalysts in enantioselective hydrogenation, C-C bond formation, and other key synthetic steps.
• Pharmaceutical Intermediate: In the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry, such as chiral amines and amino alcohols.
• Agrochemical Synthesis: For the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: In the manufacture of specialty chemicals, flavors, and fragrances where optical purity is paramount.
• Academic & Industrial R&D: As a valuable tool for methodological development in organic and organometallic chemistry.
• Chiral Resolution Agent: Potentially used in the separation of racemic mixtures via diastereomeric salt formation or chromatography.

Basic Information

Product Name	n-[(1R,2R)-2-Amino-1,2-Diphenylethyl]-2,4,6-Tris(1-Methylethyl)-Benzenesulfonamide
CAS No.	852212-92-1
Molecular Formula	C29H36N2O2S
Molecular Weight	476.68 g/mol
Synonyms	(1R,2R)-N-(2-Amino-1,2-diphenylethyl)-2,4,6-triisopropylbenzenesulfonamide; (R,R)-TsDPEN; (1R,2R)-1,2-Diphenyl-2-((2,4,6-triisopropylphenyl)sulfonamido)ethylamine; (R,R)-N-(p-Toluenesulfonyl)-1,2-diphenylethylenediamine derivative; Chiral Sulfonamide Ligand; Asymmetric Catalyst Ligand; (R,R)-DACH-Ts; (1R,2R)-N-(2,4,6-Triisopropylbenzenesulfonyl)-1,2-diphenylethylenediamine
EINECS	Contact for details

Quality Control

Our n-[(1R,2R)-2-Amino-1,2-Diphenylethyl]-2,4,6-Tris(1-Methylethyl)-Benzenesulfonamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high optical purity. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and related substances is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.