Description

2-Bromomethyl-3,4-Dihydro-2H-Chromen is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a reactive bromomethyl group on a chromene scaffold, makes it a critical intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators, leveraging its heterocyclic core.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Employed to create tagged or modified molecules for studying biological pathways and protein interactions.
• Catalyst Ligand Development: The chromene structure can be modified to create novel ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including cyclization and cross-coupling reactions.

Basic Information

Product Name	2-Bromomethyl-3,4-Dihydro-2H-Chromen
CAS No.	852181-00-1
Molecular Formula	C10H11BrO
Molecular Weight	227.10 g/mol
Synonyms	2-(Bromomethyl)-3,4-dihydro-2H-1-benzopyran; 2-(Bromomethyl)chroman; 3,4-Dihydro-2H-1-benzopyran-2-ylmethyl bromide; 2H-1-Benzopyran, 3,4-dihydro-2-(bromomethyl)-; Chroman-2-ylmethyl bromide
EINECS	Contact for details

Quality Control

Every batch of 2-Bromomethyl-3,4-Dihydro-2H-Chromen is produced and controlled under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.