Description

2-(2-Bromo-Phenyl)-2,3-Dihydro-Benzofuran-5-Carboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its benzofuran core structure and brominated phenyl substituent. This compound is of significant value for its role as a key building block in the synthesis of complex, biologically active molecules, offering a precise chemical handle for further functionalization. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, or insecticides, leveraging its heterocyclic structure.
• Organic Synthesis: Used in academic and industrial R&D for constructing complex benzofuran-based molecular architectures via cross-coupling and other advanced reactions.
• Material Science Precursor: Potential use in the development of organic electronic materials or specialty polymers due to its conjugated system.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	2-(2-Bromo-Phenyl)-2,3-Dihydro-Benzofuran-5-Carboxylic Acid Methyl Ester
CAS No.	851777-30-5
Molecular Formula	C₁₆H₁₃BrO₃
Molecular Weight	333.18 g/mol
Synonyms	Methyl 2-(2-bromophenyl)-2,3-dihydro-1-benzofuran-5-carboxylate; 5-Benzofurancarboxylic acid, 2-(2-bromophenyl)-2,3-dihydro-, methyl ester; 2-(2-Bromophenyl)-2,3-dihydrobenzofuran-5-carboxylic acid methyl ester; 851777-30-5; Methyl 2-(2-bromophenyl)-2,3-dihydrobenzofuran-5-carboxylate
EINECS	Contact for details

Quality Control

Our production of 2-(2-Bromo-Phenyl)-2,3-Dihydro-Benzofuran-5-Carboxylic Acid Methyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.