Description

(S)-n-(4-Chlorobenzylidene)-2-Methylpropane-2-Sulfinamide is a high-purity chiral sulfinamide building block, widely recognized for its utility in asymmetric synthesis. Its primary value lies in its role as a versatile chiral auxiliary and ligand, enabling the stereoselective construction of complex molecules with high enantiomeric purity. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries, where precise control over molecular chirality is critical for developing new active ingredients.

Application

• Asymmetric Synthesis: Employed as a chiral auxiliary in the stereoselective addition of nucleophiles to imines for the synthesis of enantiomerically pure amines.
• Pharmaceutical Intermediates: A key building block in the research and development of novel active pharmaceutical ingredients (APIs), particularly those requiring chiral amine motifs.
• Agrochemical Development: Used in the synthesis of chiral ligands and intermediates for crop protection agents and herbicides.
• Catalyst and Ligand Preparation: Serves as a precursor for the development of novel chiral catalysts and ligands used in transition metal catalysis.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry and process development in fine chemical manufacturing.

Basic Information

Product Name	(S)-n-(4-Chlorobenzylidene)-2-Methylpropane-2-Sulfinamide
CAS No.	851513-47-8
Molecular Formula	C11H14ClNOS
Molecular Weight	243.75 g/mol
Synonyms	(S)-(-)-N-(4-Chlorobenzylidene)-tert-Butanesulfinamide; (S)-N-(4-Chlorobenzylidene)-2-methylpropane-2-sulfinamide; (S)-N-(4-Chlorobenzylidene)-2-methylpropane-2-sulfinamide; (S)-N-(p-Chlorobenzylidene)-tert-butanesulfinamide; tert-Butanesulfinamide, N-[(4-chlorophenyl)methylene]-, (S)-; (S)-N-(4-Chlorobenzylidene)-tert-butylsulfinamide; (S)-N-(4-Chlorobenzylidene)-2-methyl-2-propanesulfinamide
EINECS	Contact for details

Quality Control

Our (S)-n-(4-Chlorobenzylidene)-2-Methylpropane-2-Sulfinamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive analytical data, including HPLC purity, chiral purity (enantiomeric excess), and identity confirmation. A detailed Certificate of Analysis (COA) is supplied with each batch, documenting compliance with our stringent specifications. Our quality management system supports the needs of cGMP and ISO-certified environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.