Description

(4R,5R)-2-Chloro-1,3-Dimethyl-4,5-Diphenyl-1-Imidazolinium Chloride is a high-purity, chiral imidazolinium salt of significant interest in advanced organic synthesis. This compound serves as a versatile chiral building block and catalyst precursor, enabling the development of enantioselective reactions critical for pharmaceutical and fine chemical manufacturing. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce stereochemical complexity into their target molecules.

Application

• Chiral Phase-Transfer Catalyst (PTC) Precursor: For enantioselective alkylation, Michael addition, and other key C-C bond-forming reactions.
• Asymmetric Synthesis Intermediate: As a building block for constructing complex, optically active nitrogen-containing heterocycles.
• Organocatalysis Research: Investigation and development of new catalytic cycles in academic and industrial research laboratories.
• Pharmaceutical Intermediate: In the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Ligand Synthesis: For the preparation of chiral ligands used in transition metal catalysis.
• Agrochemical Research: Development of enantiomerically pure herbicides, fungicides, or plant growth regulators.

Basic Information

Product Name	(4R,5R)-2-Chloro-1,3-Dimethyl-4,5-Diphenyl-1-Imidazolinium Chloride
CAS No.	851487-56-4
Molecular Formula	C₁₇H₁₈Cl₂N₂
Molecular Weight	329.24 g/mol
Synonyms	(4R,5R)-2-Chloro-1,3-dimethyl-4,5-diphenyl-4,5-dihydro-1H-imidazol-3-ium chloride; (4R,5R)-2-Chloro-1,3-dimethyl-4,5-diphenylimidazolidinium chloride; (4R,5R)-2-Chloro-1,3-dimethyl-4,5-diphenyl-2-imidazolinium chloride; Chiral Imidazolinium Salt; (R,R)-2-Chloro-1,3-dimethyl-4,5-diphenylimidazolidinium chloride
EINECS	Contact for details

Quality Control

Our (4R,5R)-2-Chloro-1,3-Dimethyl-4,5-Diphenyl-1-Imidazolinium Chloride is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity (HPLC), identity confirmation (NMR, IR), and assay determination to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.