Description

n-[3,5-Bis(Trifluoromethyl)Phenyl]-N'-(9R)-Cinchonan-9-Yl- Thiourea CAS NO 851477-19-5 is a high-purity, chiral thiourea derivative designed for advanced chemical synthesis and research. This compound is valued for its role as a sophisticated organocatalyst and a key intermediate in the development of pharmaceuticals and fine chemicals. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise molecular scaffolds for asymmetric synthesis and process development.

Application

• Asymmetric Organocatalysis: Serves as a chiral hydrogen-bond donor catalyst for enantioselective transformations, such as Michael additions and Friedel-Crafts alkylations.
• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) with complex stereochemistry.
• Ligand Synthesis: Used in the preparation of specialized ligands for metal-catalyzed reactions.
• Chemical Research & Development: A valuable tool for exploring new reaction methodologies and catalytic systems in academic and industrial R&D labs.
• Agrochemical Synthesis: Employed in the development of novel, chiral crop protection agents.
• Material Science: Investigated for the creation of functional organic materials and sensors.

Basic Information

Product Name	n-[3,5-Bis(Trifluoromethyl)Phenyl]-N'-(9R)-Cinchonan-9-Yl- Thiourea
CAS No.	851477-19-5
Molecular Formula	C₂₉H₂₅F₆N₃OS
Molecular Weight	577.59 g/mol
Synonyms	(9R)-N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(9R)-cinchonan-9-yl]thiourea; Cinchona Alkaloid Thiourea Derivative; (R)-Cinchonine-based Thiourea; 851477-19-5; Organocatalyst 851477-19-5; Chiral Thiourea Catalyst; N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(8α,9R)-cinchonan-9-yl]thiourea
EINECS	Contact for details

Quality Control

Our n-[3,5-Bis(Trifluoromethyl)Phenyl]-N'-(9R)-Cinchonan-9-Yl- Thiourea is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.