Description

(5Z)-5-(2H-Chromen-3-Ylmethylidene)-1-(1,1-Dioxidotetrahydrothiophen-3-Yl)-4-Methyl-2,6-Dioxo-1,2,5,6-Tetrahydropyridine-3-Carbonitrile CAS NO 850901-22-3 is a high-purity, non-racemic synthetic organic compound featuring a complex molecular architecture. This compound is valued as a key chiral intermediate or building block in advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral scaffold in the synthesis of potential drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a building block for constructing complex heterocyclic libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of advanced pharmaceutical intermediates (APIs).
• Agrochemical Synthesis: Acts as a precursor in the development of new active ingredients for crop protection products.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing specialized, high-value chemicals.
• Academic Research: Used in university and institutional labs for studies in organic synthesis methodology and asymmetric catalysis.

Basic Information

Product Name	(5Z)-5-(2H-Chromen-3-Ylmethylidene)-1-(1,1-Dioxidotetrahydrothiophen-3-Yl)-4-Methyl-2,6-Dioxo-1,2,5,6-Tetrahydropyridine-3-Carbonitrile
CAS No.	850901-22-3
Molecular Formula	C21H18N2O5S
Molecular Weight	410.45 g/mol
Synonyms	5-[(3Z)-3-(2H-Chromen-3-yl)prop-2-en-1-ylidene]-1-(1,1-dioxido-1,2-thiolan-3-yl)-4-methyl-2,6-dioxo-1,2,5,6-tetrahydropyridine-3-carbonitrile; (5Z)-5-(2H-1-Benzopyran-3-ylmethylene)-1-(1,1-dioxidotetrahydro-3-thienyl)-4-methyl-2,6-dioxo-1,2,5,6-tetrahydropyridine-3-carbonitrile; 3-Cyano-4-methyl-1-(1,1-dioxido-3-thiolanyl)-5-[(3Z)-3-(2H-1-benzopyran-3-yl)-2-propen-1-ylidene]-2,6(1H,5H)-pyridinedione; 850901-22-3; Chromene-pyridinedione derivative; Sulfolane-pyridine conjugate
EINECS	Contact for details

Quality Control

Our (5Z)-5-(2H-Chromen-3-Ylmethylidene)-1-(1,1-Dioxidotetrahydrothiophen-3-Yl)-4-Methyl-2,6-Dioxo-1,2,5,6-Tetrahydropyridine-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and structural confirmation via NMR and MS. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and/or moisture-sensitive; prolonged exposure to light, heat, or humidity should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0% (Area %)
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.