Description

2H-1-Benzopyran-2-One, 4-(4-Fluorophenyl)-7-Hydroxy- is a high-purity fluorinated coumarin derivative, a key advanced pharmaceutical intermediate (API) and versatile chemical building block. Its molecular structure, featuring a 4-fluorophenyl substituent and a phenolic hydroxyl group, makes it a critical precursor for synthesizing complex molecules with targeted biological activity. This compound is essential for research and development in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in therapeutic areas requiring fluorinated compounds for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Serves as a key precursor in developing new-generation pesticides and herbicides, leveraging the fluorinated aromatic system for improved efficacy.
• Organic Synthesis & Chemical Research: Used as a versatile scaffold in academic and industrial R&D for constructing complex heterocyclic compounds and fluorinated molecular libraries.
• Fluorescent Probe Development: The coumarin core structure can be utilized in developing fluorescent dyes and molecular probes for biochemical and diagnostic applications.
• Material Science Precursor: Potential use as a monomer or additive in the synthesis of specialty polymers and advanced organic materials.

Basic Information

Product Name	2H-1-Benzopyran-2-One, 4-(4-Fluorophenyl)-7-Hydroxy-
CAS No.	850881-86-6
Molecular Formula	C15H9FO3
Molecular Weight	256.23 g/mol
Synonyms	4-(4-Fluorophenyl)-7-hydroxy-2H-chromen-2-one; 7-Hydroxy-4-(4-fluorophenyl)coumarin; 4-(p-Fluorophenyl)-7-hydroxycoumarin; 7-Hydroxy-4-(4'-fluorophenyl)-2H-1-benzopyran-2-one; 850881-86-6; 4-(4-Fluorophenyl)-7-hydroxychromen-2-one
EINECS	Contact for details

Quality Control

Our 2H-1-Benzopyran-2-One, 4-(4-Fluorophenyl)-7-Hydroxy- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.