Description

Methanesulfonic Acid, 1,1,1-Trifluoro-, 3-Phenyl-1-Naphthalenyl Ester is a specialized fluorinated sulfonate ester building block of significant interest in advanced organic synthesis. This compound matters as a high-value intermediate that enables the introduction of the trifluoromethanesulfonate (triflate) group, a powerful leaving group, onto complex aromatic scaffolds. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active molecules, particularly where the unique electronic and steric properties of the naphthalene-phenyl system are required.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially for attaching complex aromatic moieties via cross-coupling reactions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the fluorinated aromatic structure can enhance biological activity and metabolic stability.
• Material Science Precursor: Acts as a monomer or functionalization agent in the creation of specialized polymers and advanced organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions such as Suzuki, Stille, and Negishi couplings due to the reactivity of the triflate group.
• Ligand and Catalyst Development: Employed in the synthesis of complex organic ligands used in asymmetric catalysis and coordination chemistry.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in research to study biological processes and interactions.

Basic Information

Product Name	Methanesulfonic Acid, 1,1,1-Trifluoro-, 3-Phenyl-1-Naphthalenyl Ester
CAS No.	850650-61-2
Molecular Formula	C₁₇H₁₁F₃O₃S
Molecular Weight	352.33 g/mol
Synonyms	3-Phenyl-1-naphthyl trifluoromethanesulfonate; 3-Phenylnaphthalen-1-yl triflate; 1-Naphthol, 3-phenyl-, triflate; Trifluoromethanesulfonic acid 3-phenyl-1-naphthalenyl ester; 3-Phenyl-1-naphthyl triflate; 3-Phenyl-1-naphthalenyl trifluoromethanesulfonate; (3-Phenylnaphthalen-1-yl) trifluoromethanesulfonate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of Methanesulfonic Acid, 1,1,1-Trifluoro-, 3-Phenyl-1-Naphthalenyl Ester is characterized and verified to meet strict purity specifications, crucial for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles by techniques such as NMR and HPLC are available upon request. We adhere to a quality management system to ensure batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.