Description

Ethyl 4-Acetyltetrahydro-2H-pyran-4-carboxylate is a high-purity, versatile heterocyclic building block with a unique fused ring structure. This compound is valued for its bifunctional nature, containing both an ester and a ketone group, which makes it a critical intermediate in sophisticated organic synthesis. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, including potential active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its heterocyclic core contributes to biological activity.
• Organic Synthesis Building Block: Serves as a versatile precursor for synthesizing complex heterocycles, spiro compounds, and other specialized fine chemicals.
• Material Science Research: Investigated as a monomer or precursor for developing novel polymers with specific thermal or optical properties.
• Academic & Industrial R&D: Employed in method development and exploratory chemistry within university laboratories and corporate R&D centers.

Basic Information

Product Name	Ethyl 4-Acetyltetrahydro-2H-pyran-4-carboxylate
CAS No.	850637-12-6
Molecular Formula	C10H16O4
Molecular Weight	200.23 g/mol
Synonyms	Ethyl 4-acetyloxane-4-carboxylate; 4-Acetyl-tetrahydro-pyran-4-carboxylic acid ethyl ester; 4-Carbethoxy-4-acetyltetrahydropyran; 4-Acetyl-4-ethoxycarbonyltetrahydropyran; Ethyl 4-acetyl-4-piperidinecarboxylate (related structure); THP-protected β-keto ester derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of Ethyl 4-Acetyltetrahydro-2H-pyran-4-carboxylate is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for sensitive R&D and scale-up processes. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.