Description

(3-Amino-4-Chlorophenyl)Boronic Acid Hydrochloride is a high-purity, functionalized boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecules. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific chlorinated aniline motifs.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs and sensors.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of boronic acid-based probes and inhibitors.
• Catalyst & Ligand Development: Serves as a starting material for synthesizing novel ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A vital raw material for custom synthesis houses serving the global life sciences market.

Basic Information

Item	Details
Product Name	(3-Amino-4-Chlorophenyl)Boronic Acid Hydrochloride
CAS No.	850568-45-5
Molecular Formula	C6H8BCl2NO2
Molecular Weight	207.86 g/mol
Synonyms	3-Amino-4-chlorobenzeneboronic acid hydrochloride; 4-Chloro-3-aminophenylboronic acid HCl; (3-Amino-4-chlorophenyl)boronic acid hydrochloride salt; B-(3-Amino-4-chlorophenyl)boronic acid hydrochloride; 850568-45-5; 3-Amino-4-chloro-benzeneboronic acid hydrochloride
EINECS	Contact for details

Quality Control

Our (3-Amino-4-Chlorophenyl)Boronic Acid Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable, and each lot is supported by a comprehensive Certificate of Analysis (COA). The COA includes data from multiple analytical techniques such as HPLC, NMR, and elemental analysis to verify identity, purity, and impurity profiles, meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.