Description

(2-Amino-4-Methoxycarbonylphenyl)Boronic Acid Pinacol Ester Hydrochloride is a high-value, multifunctional boronic ester building block essential for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific biaryl motifs.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the synthesis of sophisticated ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized to create boronic acid-based probes for sensing, imaging, and protein interaction studies.
• Scale-up and Process Chemistry: Suitable for optimization and scale-up from milligram to kilogram quantities for pre-clinical and early-phase clinical material production.

Basic Information

Item	Detail
Product Name	(2-Amino-4-Methoxycarbonylphenyl)Boronic Acid Pinacol Ester Hydrochloride
CAS No.	850567-49-6
Molecular Formula	C15H23BNO4•HCl
Molecular Weight	327.62 g/mol (Free base: 291.16 g/mol)
Synonyms	2-Amino-4-(Methoxycarbonyl)phenylboronic Acid Pinacol Ester Hydrochloride; Methyl 2-Amino-4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate Hydrochloride; 4-Carbomethoxy-2-aminophenylboronic Acid Pinacol Ester HCl; B-[2-Amino-4-(Methoxycarbonyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Hydrochloride; CAS 850567-49-6; Boronic Ester Building Block 850567-49-6; Aryl Boronate Ester Hydrochloride Salt
EINECS	Contact for details

Quality Control

Our (2-Amino-4-Methoxycarbonylphenyl)Boronic Acid Pinacol Ester Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR (¹H and ¹³C), and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full analytical data are provided for each lot to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or in a dry environment to maintain stability. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥95.0% (Area %)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.