Description

(S)-3-(2,6-Diisopropylphenyl)-1-(1-Hydroxy-3-Methylbutan-2-Yl)-4,5-Dihydro-1H-Imidazol-3-Ium Hexafluorophosphate(V) is a high-purity, chiral imidazolium salt primarily utilized as a sophisticated catalyst or ligand precursor in advanced organic synthesis. Its value lies in enabling highly selective and efficient chemical transformations, which are critical for producing complex molecules with defined stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for asymmetric synthesis and the development of novel active pharmaceutical ingredients (APIs).

Application

• Asymmetric Catalysis: Serving as a key precursor for chiral N-heterocyclic carbene (NHC) ligands in transition metal-catalyzed reactions, including cross-couplings and enantioselective hydrogenations.
• Pharmaceutical Intermediate Synthesis: Enabling the construction of complex, stereochemically defined molecular scaffolds for novel drug candidates and active pharmaceutical ingredients (APIs).
• Organocatalysis: Potential use as an organocatalyst or as a structural motif in the design of new organocatalytic systems for green chemistry applications.
• Material Science Research: Acting as a building block for chiral ionic liquids or functionalized polymers with potential applications in advanced materials.
• Methodology Development: A valuable tool for academic and industrial researchers developing new synthetic methodologies that require precise stereocontrol.
• Fine Chemical Production: Facilitating the synthesis of high-value specialty chemicals, flavors, and fragrances where enantiopurity is paramount.

Basic Information

Product Name	(S)-3-(2,6-Diisopropylphenyl)-1-(1-Hydroxy-3-Methylbutan-2-Yl)-4,5-Dihydro-1H-Imidazol-3-Ium Hexafluorophosphate(V)
CAS No.	850469-08-8
Molecular Formula	C20H33F6N2O2P
Molecular Weight	478.45 g/mol
Synonyms	(S)-1-(1-Hydroxy-3-methylbutan-2-yl)-3-(2,6-diisopropylphenyl)-4,5-dihydro-1H-imidazol-3-ium hexafluorophosphate; (S)-3-(2,6-Diisopropylphenyl)-1-(1-hydroxy-3-methylbutan-2-yl)-4,5-dihydro-1H-imidazol-3-ium hexafluorophosphate; Chiral Imidazolium Hexafluorophosphate Salt; Precursor to Chiral NHC Ligand; (S)-IPr*·HCl Precursor Analog; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (S)-3-(2,6-Diisopropylphenyl)-1-(1-Hydroxy-3-Methylbutan-2-Yl)-4,5-Dihydro-1H-Imidazol-3-Ium Hexafluorophosphate(V) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity, correct stereochemistry, and consistent performance. Standard quality checks include chiral purity analysis (HPLC or SFC), identity confirmation (NMR, IR), and quantification of key impurities. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure (1H NMR, 13C NMR, 31P NMR)
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC/SFC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.