Description

1-[(S)-1-(Hydroxymethyl)-2-Methylpropyl]-3-(2,4,6-Trimethylphenyl)-4,5-Dihydro-1H-Imidazolium Hexafluorophosphate is a high-purity, chiral imidazolium salt primarily utilized as a specialized catalyst or ligand in advanced organic synthesis. Its value lies in enabling precise stereoselective transformations, which are critical for producing complex molecules with high enantiomeric purity. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries developing novel active ingredients and high-value intermediates.

Application

• Asymmetric Catalysis: Serving as a chiral ligand or catalyst precursor in transition metal-catalyzed reactions such as hydrogenation, hydrosilylation, and cross-coupling.
• Pharmaceutical Intermediate Synthesis: Facilitating the stereoselective construction of chiral centers in the development of new Active Pharmaceutical Ingredients (APIs).
• Agrochemical Research: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Enabling the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial R&D: A key reagent for methodological development in organic chemistry and process optimization studies.
• Material Science: Potential application in the synthesis of chiral ionic liquids or advanced polymeric materials.

Basic Information

Product Name	1-[(S)-1-(Hydroxymethyl)-2-Methylpropyl]-3-(2,4,6-Trimethylphenyl)-4,5-Dihydro-1H-Imidazolium Hexafluorophosphate
CAS No.	850469-00-0
Molecular Formula	C₁₇H₂₇F₆N₂O₂P
Molecular Weight	460.37 g/mol
Synonyms	(S)-1-[(1-Hydroxymethyl-2-methylpropyl)]-3-(2,4,6-trimethylphenyl)-4,5-dihydro-1H-imidazol-3-ium hexafluorophosphate; Chiral Imidazolium Hexafluorophosphate Salt; (S)-Imidazolium PF₆ Salt; (S)-1-(1-Hydroxy-2-methylpropyl)-3-mesityl-4,5-dihydroimidazolium Hexafluorophosphate; (S)-Mesityl-Imidazolinium Hexafluorophosphate Derivative; (S)-H-Met-Imidazolium PF₆; (S)-1-(2-Methyl-1-hydroxypropyl)-3-(2,4,6-trimethylphenyl)-2,3-dihydro-1H-imidazol-3-ium Hexafluorophosphate
EINECS	Contact for details

Quality Control

Our production of this chiral ionic compound adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity, critical for catalytic performance. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, enantiomeric excess, and impurity profile is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under a dry, inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.