Description

2-(4-Bromo-Phenoxymethyl)-[1,3]Dioxolane is a specialized organic building block featuring a brominated aromatic ether moiety protected as a dioxolane acetal. This compound is valued for its role as a versatile synthetic intermediate, enabling controlled reactivity in complex organic synthesis. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for constructing novel active molecules and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a protected aldehyde functionality and a bromoaryl handle for cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the bromophenoxy moiety is a common structural motif.
• Liquid Crystal & OLED Material Research: Serves as a precursor in the development of advanced organic electronic materials due to its rigid, brominated aromatic structure.
• Polymer Chemistry: Can be incorporated as a monomer or chain modifier to introduce specific functional groups into polymer backbones for specialty plastics and resins.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Sonogashira couplings to form complex biaryl systems.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory synthesis in university and CRO laboratory settings.

Basic Information

Product Name	2-(4-Bromo-Phenoxymethyl)-[1,3]Dioxolane
CAS No.	850348-66-2
Molecular Formula	C10H11BrO3
Molecular Weight	259.10 g/mol
Synonyms	4-Bromophenyl (2,2-dimethyl-1,3-dioxolan-4-yl)methyl ether; 1,3-Dioxolane, 2-[(4-bromophenoxy)methyl]-; 2-[(4-Bromophenoxy)methyl]-1,3-dioxolane; (4-Bromophenoxymethyl)-1,3-dioxolane; p-Bromophenyl 2,2-dimethyl-1,3-dioxolan-4-ylmethyl ether; Acetal-protected 4-bromobenzaldehyde derivative
EINECS	Contact for details

Quality Control

Our 2-(4-Bromo-Phenoxymethyl)-[1,3]Dioxolane is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.