Description

Potassium 2-Hydroxyphenyltrifluoroborate is an organoboron reagent, specifically a potassium aryltrifluoroborate salt, widely used in modern synthetic chemistry. This compound matters as a stable, air- and moisture-tolerant alternative to boronic acids, enabling key carbon-carbon bond-forming reactions under mild conditions. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key building block for the palladium-catalyzed cross-coupling with aryl/vinyl halides to form biaryl and styrenyl structures, crucial in pharmaceutical intermediate synthesis.
• Pharmaceutical Intermediate Manufacturing: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing phenolic or biphenyl motifs.
• Agrochemical Synthesis: Employed in creating novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands for transition metal catalysis and other functional materials.
• Material Science Research: Utilized in the development of organic electronic materials, polymers, and liquid crystals where precise aromatic coupling is essential.
• Chemical Biology & Probe Synthesis: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes for biological imaging and target identification.

Basic Information

Product Name	Potassium 2-Hydroxyphenyltrifluoroborate
CAS No.	850313-92-7
Molecular Formula	C6H5BF3KO
Molecular Weight	187.91 g/mol
Synonyms	Potassium (2-Hydroxyphenyl)trifluoroborate; 2-Hydroxyphenyltrifluoroborate Potassium Salt; Potassium 2-Hydroxybenzenetrifluoroborate; (2-Hydroxyphenyl)trifluoroboronic Acid Potassium Salt; 2-Hydroxybenzeneboronic Acid, Trifluoro-, Potassium Salt; Potassium 2-Hydroxyphenyl-BF3; Potassium o-Hydroxyphenyltrifluoroborate; Potassium Salicyltrifluoroborate
EINECS	Contact for details

Quality Control

Our Potassium 2-Hydroxyphenyltrifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 11B, 19F) and HPLC analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
NMR Purity (1H)	≥ 95%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.