Description

Potassium (2,4-Dimethylphenyl)Trifluoroborate is an organoboron reagent belonging to the potassium trifluoroborate salt class, valued for its enhanced stability and handling properties compared to boronic acids. This compound serves as a crucial coupling partner in Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for forming carbon-carbon bonds in complex molecule synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing biaryl and heterobiaryl scaffolds.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing complex drug candidates, especially those containing substituted biphenyl or aryl-heteroaryl motifs.
• Agrochemical Development: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and conductive polymers, where precise molecular architecture is critical.
• Chemical Biology & Probe Development: Facilitates the labeling and modification of biomolecules or the creation of molecular probes for diagnostic applications.
• Catalysis & Ligand Development: Acts as a substrate in catalyst screening and the development of new phosphine ligands or catalytic systems.
• Custom Synthesis & Contract Manufacturing: Serves as a specialized reagent for custom synthesis houses (CDMOs) producing high-value intermediates for clients.

Basic Information

Product Name	Potassium (2,4-Dimethylphenyl)Trifluoroborate
CAS No.	850245-50-0
Molecular Formula	C8H9BF3K
Molecular Weight	212.06 g/mol
Synonyms	Potassium (2,4-Dimethylphenyl)trifluoroboronate; Potassium 2,4-Dimethylphenyltrifluoroborate; (2,4-Dimethylphenyl)trifluoroborate Potassium Salt; 2,4-Dimethylphenyltrifluoroboronic Acid Potassium Salt; 2,4-Dimethylphenyl-BF3K; 850245-50-0; Potassium (2,4-Xylyl)trifluoroborate
EINECS	Contact for details

Quality Control

Every batch of Potassium (2,4-Dimethylphenyl)Trifluoroborate is produced and tested under strict quality management protocols. We provide comprehensive analytical data including NMR (¹H, ¹³C, ¹⁹F, ¹¹B) and HPLC purity to ensure identity, strength, and quality. Certificates of Analysis (COA) detailing all specifications are available upon request and are aligned with cGMP principles where applicable for advanced intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under inert atmosphere (argon or nitrogen) in a moisture-controlled environment to maintain stability and purity. Keep away from strong acids and strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
¹H NMR Assay	≥ 95%
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.