Description

4-(tert-Butyl)-3-Fluoroaniline is a high-purity fluorinated aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique steric and electronic properties imparted by the tert-butyl and fluorine substituents, which are essential for fine-tuning the performance of target molecules. This intermediate is particularly needed by manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of fluorinated drug candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity, metabolic stability, and lipophilicity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic diamines and other monomers used in high-performance electronic display materials.
• Polymer & Resin Modifier: Incorporated into specialty polymers to improve thermal stability, chemical resistance, and optical properties.
• Dye & Pigment Intermediate: Utilized in the synthesis of complex, light-fast fluorinated dyes and organic pigments.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and material properties.

Basic Information

Product Name	4-(tert-Butyl)-3-Fluoroaniline
CAS No.	850040-16-3
Molecular Formula	C10H14FN
Molecular Weight	167.23 g/mol
Synonyms	3-Fluoro-4-tert-butylaniline; 4-tert-Butyl-3-fluoroaniline; 3-Fluoro-4-(1,1-dimethylethyl)benzenamine; 1-tert-Butyl-2-fluoro-4-aminobenzene; Benzenamine, 3-fluoro-4-(1,1-dimethylethyl)-; 3-Fluoro-4-(tert-butyl)aniline; 4-(tert-Butyl)-3-fluorobenzenamine
EINECS	Contact for details

Quality Control

Our 4-(tert-Butyl)-3-Fluoroaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.