Description

5,7-Bis-(Benzyloxy)-α-(4-(Benzyloxy)Phenyl)-3-[3,4-Di-o-Acetyl-α-o-Acetyl-α-L-Rhamnopyranosyloxyl]-4H-Chromen-4-One is a complex, high-purity flavonoid glycoside derivative, serving as a critical advanced intermediate in pharmaceutical research and development. Its precise molecular architecture makes it an invaluable building block for synthesizing novel therapeutic agents, particularly in oncology and anti-inflammatory drug discovery. This compound is essential for R&D chemists and process development scientists in the pharmaceutical and biotechnology industries who require reliable, high-quality intermediates for lead optimization and scale-up studies.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development of novel flavonoid-based drug candidates targeting various disease pathways.
• Oncology Research: Used in the synthesis of potential chemotherapeutic agents and targeted cancer therapies due to its modifiable chromen-4-one core structure.
• Anti-inflammatory Drug Development: Serves as a scaffold for creating compounds with potential COX-2 inhibition or other anti-inflammatory mechanisms of action.
• Biochemical Tool Compound: Employed in academic and industrial research to study enzyme interactions, receptor binding, and cellular signaling pathways.
• Process Chemistry & Scale-Up: Used by process development teams to establish robust, scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	5,7-Bis-(Benzyloxy)-α-(4-(Benzyloxy)Phenyl)-3-[3,4-Di-o-Acetyl-α-o-Acetyl-α-L-Rhamnopyranosyloxyl]-4H-Chromen-4-One
CAS No.	849938-27-8
Molecular Formula	C52H48O14
Molecular Weight	896.93 g/mol
Synonyms	3-[(2,3,4-Tri-O-acetyl-α-L-rhamnopyranosyl)oxy]-5,7-bis(phenylmethoxy)-2-[4-(phenylmethoxy)phenyl]-4H-1-benzopyran-4-one; 5,7-Dibenzyloxy-α-(4-benzyloxyphenyl)-3-(2,3,4-tri-O-acetyl-α-L-rhamnopyranosyloxy)-4H-chromen-4-one; Flavonoid rhamnoside derivative; Benzylated flavonoid glycoside intermediate; 849938-27-8; 4H-1-Benzopyran-4-one, 3-[(2,3,4-tri-O-acetyl-α-L-rhamnopyranosyl)oxy]-5,7-bis(phenylmethoxy)-2-[4-(phenylmethoxy)phenyl]-
EINECS	Contact for details

Quality Control

Every batch of our 5,7-Bis-(Benzyloxy)-α-(4-(Benzyloxy)Phenyl)-3-[3,4-Di-o-Acetyl-α-o-Acetyl-α-L-Rhamnopyranosyloxyl]-4H-Chromen-4-One undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality systems are designed to meet the stringent requirements of pharmaceutical R&D and cGMP standards for advanced intermediates. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), identity confirmation (by NMR and IR), and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccant use and storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.