Description

4-Oxo-2-Spiro(n-Boc-Piperidine-4-Yl)-Benzopyran is a high-value, advanced pharmaceutical intermediate featuring a complex spirocyclic and benzopyran scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel drug candidates. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents, particularly in central nervous system (CNS) and oncology-related fields.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex bioactive molecules and potential drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Protease Inhibitor Development: The structural motifs present are valuable for designing inhibitors targeting specific enzymatic pathways.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological processes and target validation.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs performing bespoke synthetic routes for clients.
• Academic Research: Employed in university and institutional labs for methodological development and exploring new chemical spaces.

Basic Information

Item	Details
Product Name	4-Oxo-2-Spiro(n-Boc-Piperidine-4-Yl)-Benzopyran
CAS No.	849928-22-9
Molecular Formula	C19H23NO5
Molecular Weight	345.39 g/mol
Synonyms	2-(1-(tert-Butoxycarbonyl)piperidin-4-yl)-4H-chromen-4-one; 4-Oxo-2-spiro(1-N-Boc-piperidine-4-yl)-4H-chromene; 2-(1-Boc-piperidin-4-yl)-4H-chromen-4-one; 2-(N-Boc-4-piperidyl)-4-chromone; tert-Butyl 4-(4-oxo-4H-chromen-2-yl)piperidine-1-carboxylate; 849928-22-9; 4H-1-Benzopyran-4-one, 2-(1-[(1,1-dimethylethoxy)carbonyl]-4-piperidinyl)-
EINECS	Contact for details

Quality Control

Every batch of 4-Oxo-2-Spiro(n-Boc-Piperidine-4-Yl)-Benzopyran is produced under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to guarantee it meets your specific research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.