Description

(3R)-2,3-Dihydro-5,7-Dihydroxy-3-[(4-Hydroxyphenyl)Methyl]-4H-1-Benzopyran-4-One is a high-purity, optically active flavanone derivative of significant interest in advanced research and development. This compound serves as a critical chiral building block and reference standard for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams, nutraceutical formulators, and academic researchers focused on natural product chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral precursor for the synthesis of potential therapeutic agents targeting inflammation, metabolic disorders, and oxidative stress.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of flavonoid-based products and natural extracts.
• Nutraceutical Research: Investigated for its potential bioactive properties in the development of advanced dietary supplements and functional food ingredients.
• Biochemical Research: Employed in enzymatic and receptor-binding studies to explore structure-activity relationships (SAR) within the flavanone class.
• Cosmeceutical Development: Studied for its antioxidant properties in the formulation of advanced skincare and anti-aging products.

Basic Information

Product Name	(3R)-2,3-Dihydro-5,7-Dihydroxy-3-[(4-Hydroxyphenyl)Methyl]-4H-1-Benzopyran-4-One
CAS No.	849727-88-4
Molecular Formula	C₁₆H₁₄O₅
Molecular Weight	286.28 g/mol
Synonyms	(3R)-5,7-Dihydroxy-3-(4-hydroxybenzyl)chroman-4-one; (R)-3-(4-Hydroxybenzyl)-5,7-dihydroxychroman-4-one; (R)-Sakuranetin (fully hydrogenated); (3R)-Leucocyanidin derivative; (R)-Flavanone-3-(4-hydroxybenzyl) derivative; (3R)-Dihydro-5,7-dihydroxy-3-(4-hydroxybenzyl)-4H-chromen-4-one; (R)-3-(p-Hydroxybenzyl)-5,7-dihydroxy-2,3-dihydrochromen-4-one
EINECS	Contact for details

Quality Control

Every batch of our (3R)-2,3-Dihydro-5,7-Dihydroxy-3-[(4-Hydroxyphenyl)Methyl]-4H-1-Benzopyran-4-One is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including HPLC chromatograms and chiral purity data, to ensure compliance with research-grade specifications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.