Description

Trifluoromethanesulfonic Acid 6,7-Dimethoxyquinolin-4-Yl Ester is a high-purity, advanced pharmaceutical intermediate and chemical building block. This compound is valued for its role as a versatile trifluoromethanesulfonate (triflate) ester derivative, enabling critical coupling and functionalization reactions in complex organic synthesis. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those containing the quinoline scaffold for potential therapeutic applications.
• Agrochemical Synthesis: Used in research and development for creating novel pesticides and herbicides, leveraging its reactive triflate group.
• Cross-Coupling Reactions: Serves as an excellent substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) due to the superior leaving group ability of the triflate moiety.
• Chemical Building Block: Employed in organic synthesis for the introduction of the 6,7-dimethoxyquinolin-4-yl group into target molecules.
• Material Science Research: Investigated as a monomer or functional component in the development of specialty polymers and advanced materials.

Basic Information

Product Name	Trifluoromethanesulfonic Acid 6,7-Dimethoxyquinolin-4-Yl Ester
CAS No.	849217-54-5
Molecular Formula	C₁₂H₁₀F₃NO₅S
Molecular Weight	337.27 g/mol
Synonyms	6,7-Dimethoxyquinolin-4-yl Trifluoromethanesulfonate; 6,7-Dimethoxy-4-quinolyl Triflate; 4-(Trifluoromethanesulfonyloxy)-6,7-dimethoxyquinoline; Trifluoromethanesulfonic Acid 6,7-Dimethoxy-4-quinolyl Ester; 6,7-Dimethoxyquinoline-4-triflate; 6,7-Dimethoxy-4-quinolinyl Triflate; 4-Quinolinol, 6,7-dimethoxy-, 4-trifluoromethanesulfonate
EINECS	Contact for details

Quality Control

Our Trifluoromethanesulfonic Acid 6,7-Dimethoxyquinolin-4-Yl Ester is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.