Description

7-Hydroxy-8-{[4-(2-Hydroxyethyl)Piperazin-1-Yl]Methyl}-3-Phenyl-2-(Trifluoromethyl)-4H-Chromen-4-One is a high-purity, complex heterocyclic compound that serves as a critical advanced intermediate in pharmaceutical research and development. Its unique molecular architecture, featuring a chromen-4-one core substituted with a trifluoromethyl group and a functionalized piperazine moiety, makes it a valuable scaffold for medicinal chemistry. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probe: Serves as a starting material for developing molecular probes to study enzyme function or protein interactions.
• Process Chemistry Development: Employed in scaling up synthetic routes for active pharmaceutical ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Library Synthesis: Used in combinatorial chemistry to generate diverse compound libraries for high-throughput screening.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	7-Hydroxy-8-{[4-(2-Hydroxyethyl)Piperazin-1-Yl]Methyl}-3-Phenyl-2-(Trifluoromethyl)-4H-Chromen-4-One
CAS No.	848745-30-2
Molecular Formula	C24H23F3N2O4
Molecular Weight	460.45 g/mol
Synonyms	7-Hydroxy-8-[(4-(2-hydroxyethyl)piperazin-1-yl)methyl]-3-phenyl-2-(trifluoromethyl)-4H-chromen-4-one; 2-(Trifluoromethyl)-3-phenyl-7-hydroxy-8-[(4-(2-hydroxyethyl)-1-piperazinyl)methyl]-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one, 7-hydroxy-8-[[4-(2-hydroxyethyl)-1-piperazinyl]methyl]-3-phenyl-2-(trifluoromethyl)-; 848745-30-2; Chromen-4-one derivative; Trifluoromethyl chromone piperazine derivative.
EINECS	Contact for details

Quality Control

Our 7-Hydroxy-8-{[4-(2-Hydroxyethyl)Piperazin-1-Yl]Methyl}-3-Phenyl-2-(Trifluoromethyl)-4H-Chromen-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment. We can support development with custom purity grades and specifications tailored to your project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.