Description

5-Methyl-2-(Tributylstannyl)Thiazole is a specialized organotin reagent featuring a functionalized thiazole heterocycle. This compound is a critical building block in modern synthetic organic chemistry, particularly for Stille cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for developing new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those containing complex thiazole-based heterocycles for therapeutic applications.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides where the thiazole moiety imparts specific biological activity.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysis, and other functional organic molecules.
• Stille Cross-Coupling Reactions: Serves as a versatile organotin coupling partner for the formation of carbon-carbon bonds with a wide range of organic electrophiles.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds and molecular probes for biochemical and diagnostic research.
• Academic & Industrial R&D: A valuable reagent for method development and exploratory synthesis in both university laboratories and corporate R&D centers.

Basic Information

Product Name	5-Methyl-2-(Tributylstannyl)Thiazole
CAS No.	848613-91-2
Molecular Formula	C16H31NSSn
Molecular Weight	388.19 g/mol
Synonyms	2-(Tributylstannyl)-5-methylthiazole; Tributyl(5-methyl-2-thiazolyl)stannane; 5-Methyl-2-thiazolyltributyltin; 5-Methyl-2-tributylstannanyl-1,3-thiazole; Stannane, tributyl(5-methyl-2-thiazolyl)-; 848613-91-2
EINECS	Contact for details

Quality Control

Every batch of 5-Methyl-2-(Tributylstannyl)Thiazole is manufactured and analyzed under strict quality management protocols to ensure consistency and reliability for sensitive synthetic applications. Our products undergo rigorous quality testing, including NMR, HPLC, and elemental analysis, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. Keep the container in a cool, dry, well-ventilated place, away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Tin (Sn) Content	Calculated from formula

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.