Description

5-Iodo-Pyran-2-One is a halogenated heterocyclic compound with the CAS registry number 847822-70-2, serving as a versatile and valuable synthetic building block in advanced organic chemistry. Its core value lies in its reactive iodine substituent, which enables efficient cross-coupling reactions and functional group transformations critical for constructing complex molecular architectures. This intermediate is particularly essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry research for targeted therapies.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides requiring specific halogenated heterocyclic cores.
• Material Science Research: Serves as a precursor for organic electronic materials, such as charge-transport molecules or ligands for metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: The iodine atom facilitates pivotal reactions like Suzuki, Stille, and Negishi couplings for carbon-carbon bond formation.
• Chemical Biology Probes: Utilized in creating tagged molecules or probes for studying biological pathways and enzyme functions.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.

Basic Information

Product Name	5-Iodo-Pyran-2-One
CAS No.	847822-70-2
Molecular Formula	C5H3IO2
Molecular Weight	237.98 g/mol
Synonyms	5-Iodopyran-2-one; 5-Iodo-2H-pyran-2-one; 2H-Pyran-2-one, 5-iodo-; 5-Iodopyran-2(1H)-one; 5-Iodo-2-pyranone; 5-Iodo-2H-pyran-2(1H)-one
EINECS	Contact for details

Quality Control

Our 5-Iodo-Pyran-2-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and NMR/IR for structural confirmation, to meet the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee supply reliability and product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature, the container should be kept in the original packaging or an opaque secondary container until use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.