Description

Aes-350 is a high-purity specialty chemical identified by CAS NO 847249-57-4, widely utilized as a critical intermediate in advanced pharmaceutical synthesis and functional material development. Its consistent molecular integrity and batch-to-batch reproducibility make it essential for applications demanding stringent quality control and regulatory traceability. Pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and electronic materials manufacturers rely on Aes-350 CAS NO 847249-57-4 for precision-critical syntheses where impurity profiles directly impact final product safety and performance.

Application

• Key intermediate in the synthesis of angiotensin receptor blockers (ARBs) and other cardiovascular therapeutics
• Building block for photoactive polymers used in OLED display materials and organic semiconductors
• Reagent in the preparation of chiral ligands for asymmetric catalysis in fine chemical manufacturing
• Component in high-performance coating additives for corrosion-resistant industrial finishes
• Functional monomer in crosslinkable hydrogel formulations for controlled drug delivery systems
• Stabilizing agent in nanoparticle surface functionalization for diagnostic imaging agents

Basic Information

Product Name	Aes-350
CAS No.	847249-57-4
Molecular Formula	C15H12F3N3O2
Molecular Weight	347.27 g/mol
Synonyms	3-(Trifluoromethyl)-N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)benzamide; Aes-350; TRIFLUOROMETHYL BENZAMIDE BORONATE; 3-(Trifluoromethyl)benzoyl-4-aminophenylboronic acid ester; N-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-3-(trifluoromethyl)benzamide; TFM-BPBA; Boronic acid derivative Aes-350; 3-CF3-Benzoyl-4-APB
EINECS	Not listed (not yet assigned)

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. All batches conform to ISO 9001:2015 certified manufacturing protocols, with purity verified by HPLC (>99.5% assay) and identity confirmed via FT-IR and 1H-NMR spectroscopy. Impurity profiling meets ICH Q3A(R2) guidelines for pharmaceutical intermediates, and residual solvent analysis complies with USP & Ph. Eur. general chapter <467>.

Storage

Preserve in a tightly closed container, protected from light. Store at 15–25°C in a dry, well-ventilated area. Due to its hygroscopic nature, minimize exposure to ambient humidity; use desiccant-containing secondary packaging during long-term storage. Avoid contact with strong alkalis or fluoride sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Assay (HPLC)	≥99.5%
Identification (IR)	Conforms to reference standard
Identification (1H-NMR)	Conforms to reference standard
Residue on Ignition	≤0.1%
Water (Karl Fischer)	≤0.5%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Single impurity ≤0.3%; Total impurities ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.