Description

4,5-Diiodopyridazin-3(2H)-One is a high-value, halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile precursor in the development of novel pharmaceutical intermediates and agrochemicals, where its diiodo-substituted pyridazinone core enables selective functionalization. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors or other biologically active heterocycles.
• Agrochemical Research: Serves as a building block for developing new active ingredients for crop protection products, leveraging its halogenated structure.
• Organic Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitution reactions to introduce complex functionalities.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials or ligands for catalytic systems due to its electron-deficient heterocyclic structure.
• Chemical Biology Probe Development: Can be used to create tagged molecules for studying biological pathways and protein interactions.

Basic Information

Product Name	4,5-Diiodopyridazin-3(2H)-One
CAS No.	847026-46-4
Molecular Formula	C4H2I2N2O
Molecular Weight	387.88 g/mol
Synonyms	3(2H)-Pyridazinone, 4,5-diiodo-; 4,5-Diiodo-2,3-dihydropyridazin-3-one; 4,5-Diiodo-3(2H)-pyridazinone; 4,5-Diiodopyridazin-3-ol; 4,5-Diiodo-1,2-dihydropyridazine-3,6-dione (tautomer); DIHP; CAS 847026-46-4
EINECS	Contact for details

Quality Control

Our 4,5-Diiodopyridazin-3(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.