Description

1-(Trimethylsilyl)-4-Chloro-3-Methylbenzene is a high-purity organosilicon intermediate characterized by its unique trimethylsilyl-protected aromatic structure. This compound is critical for advanced organic synthesis, offering a protected functional group that enables precise chemical transformations in sensitive reaction environments. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly where the silyl group acts as a protective moiety or directs regioselectivity.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogen and silyl functionalities for creating diverse bioactive molecules.
• Liquid Crystal & OLED Material Precursor: Functions as a starting material for synthesizing advanced organic electronic materials and liquid crystal compounds due to its stable aromatic core.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) for carbon-carbon bond formation in complex molecule assembly.
• Organometallic Chemistry: Employed in the preparation of organometallic reagents and catalysts for specialized synthetic applications.
• Polymer Modification: Used to introduce silyl and chloro functionalities into polymer backbones to alter material properties like solubility, thermal stability, and reactivity.

Basic Information

Product Name	1-(Trimethylsilyl)-4-Chloro-3-Methylbenzene
CAS No.	845823-24-7
Molecular Formula	C10H15ClSi
Molecular Weight	198.76 g/mol
Synonyms	4-Chloro-3-methyl-1-(trimethylsilyl)benzene; 1-Chloro-2-methyl-4-(trimethylsilyl)benzene; 4-Chloro-3-methylphenyltrimethylsilane; (4-Chloro-3-methylphenyl)trimethylsilane; TMS-Protected 4-Chloro-3-methylbenzene; Trimethyl(4-chloro-3-methylphenyl)silane; Benzene, 1-chloro-2-methyl-4-(trimethylsilyl)-; CAS 845823-24-7
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is validated using advanced analytical techniques including GC, HPLC, and NMR to guarantee identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are available upon request. We adhere to a quality management system to ensure traceability and reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and moisture. For long-term storage, consider under an inert atmosphere such as nitrogen or argon to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.5%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.