Description

3-Chloro-5-(Trifluoromethyl)Pyridazine is a high-value, multi-functional heterocyclic building block essential for advanced chemical synthesis. Its unique structure, featuring both chloro and trifluoromethyl substituents on the pyridazine ring, makes it a critical intermediate for introducing specific physicochemical properties into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced efficacy and stability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and electronic materials.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis in discovery programs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and complex molecules under cGMP conditions.

Basic Information

Product Name	3-Chloro-5-(trifluoromethyl)pyridazine
CAS No.	845617-99-4
Molecular Formula	C5H2ClF3N2
Molecular Weight	182.53 g/mol
Synonyms	3-Chloro-5-(trifluoromethyl)pyridazine; 5-(Trifluoromethyl)-3-chloropyridazine; 3-Chloro-5-trifluoromethylpyridazine; Pyridazine, 3-chloro-5-(trifluoromethyl)-; 845617-99-4; 3-Chloro-5-(trifluoromethyl)-1,2-diazine
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our fine chemical intermediates. Each batch of 3-Chloro-5-(Trifluoromethyl)Pyridazine is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. Our quality system supports development and commercial supply, with capabilities to meet specific customer requirements for pharmaceutical (cGMP) and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.