Description

cis-4-(1,1-Dimethylethyl)-1-Hydroxycyclohexanecarboxylic Acid is a high-purity, functionalized cyclohexane derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in the precise stereochemistry and the combination of a carboxylic acid and a tertiary butyl-substituted hydroxyl group, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and metabolic disease research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and plant growth regulators where specific stereochemistry impacts biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & R&D: A valuable compound for methodological studies in organic chemistry and material science research.

Basic Information

Product Name	cis-4-(1,1-Dimethylethyl)-1-Hydroxycyclohexanecarboxylic Acid
CAS No.	845508-40-9
Molecular Formula	C11H20O3
Molecular Weight	200.27 g/mol
Synonyms	cis-4-tert-Butyl-1-hydroxycyclohexanecarboxylic Acid; 4-(tert-Butyl)-1-hydroxycyclohexanecarboxylic Acid (cis-); (1r,4r)-4-(tert-Butyl)-1-hydroxycyclohexanecarboxylic Acid; 4-tert-Butyl-1-hydroxy-cyclohexanecarboxylic acid; cis-4-tert-Butyl-1-hydroxy-1-cyclohexanecarboxylic Acid; 845508-40-9; Cyclohexanecarboxylic acid, 4-(1,1-dimethylethyl)-1-hydroxy-, cis-
EINECS	Contact for details

Quality Control

Our cis-4-(1,1-Dimethylethyl)-1-Hydroxycyclohexanecarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% cis-isomer
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.