Description

4-(2-Chloro-5-Fluorophenyl)Benzoic Acid is a high-purity fluorinated biphenyl carboxylic acid derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its precise molecular architecture, which enables the synthesis of complex active pharmaceutical ingredients (APIs) with targeted therapeutic effects. This compound is essential for R&D and production teams in the pharmaceutical and agrochemical sectors, particularly those developing novel small-molecule drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the fluorophenyl moiety for enhanced bioactivity.
• Liquid Crystal Material Precursor: Serves as a starting material for synthesizing fluorinated liquid crystal compounds used in display technologies.
• Organic Electronic Material Research: Employed in the development of organic semiconductors and charge-transport materials due to its conjugated biphenyl system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom API synthesis projects.
• Academic & Industrial R&D: Used in research laboratories for method development and exploring new chemical entities in medicinal chemistry.

Basic Information

Product Name	4-(2-Chloro-5-Fluorophenyl)Benzoic Acid
CAS No.	844878-86-0
Molecular Formula	C13H8ClFO2
Molecular Weight	250.65 g/mol
Synonyms	[2-Chloro-5-fluorophenyl]-4-benzoic acid; 4-(2-Chloro-5-fluorophenyl)benzoic acid; Benzoic acid, 4-(2-chloro-5-fluorophenyl)-; 2-Chloro-5-fluoro-4'-carboxybiphenyl; 4'-Carboxy-2-chloro-5-fluorobiphenyl; Biphenyl-4-carboxylic acid, 2'-chloro-5'-fluoro-
EINECS	Contact for details

Quality Control

Our production of 4-(2-Chloro-5-Fluorophenyl)Benzoic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, and NMR for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.