Description

2-Bromo-3-(3-Fluoro-4-Methoxyphenyl)-1-Propene is a high-value, halogenated organic building block of significant interest in advanced synthetic chemistry. Its unique molecular structure, featuring bromine and fluorine substituents on a propenylbenzene scaffold, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where precise structural modification is critical.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Used in the research and development of specialty polymers and liquid crystals, where its halogenated aromatic core can influence material properties.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.
• Fluorine Chemistry Studies: Acts as a model compound in medicinal chemistry to study the effects of fluorine substitution on bioactivity and metabolic stability.
• Fine Chemical Synthesis: Employed in custom and contract synthesis for producing high-value, low-volume specialty chemicals for research and development.

Basic Information

Product Name	2-Bromo-3-(3-Fluoro-4-Methoxyphenyl)-1-Propene
CAS No.	842140-40-3
Molecular Formula	C10H10BrFO
Molecular Weight	245.09 g/mol
Synonyms	1-Propene, 2-bromo-3-(3-fluoro-4-methoxyphenyl)-; 2-Bromo-3-(3-fluoro-4-methoxyphenyl)prop-1-ene; 3-(3-Fluoro-4-methoxyphenyl)-2-bromoprop-1-ene; (2-Bromoallyl)(3-fluoro-4-methoxyphenyl)methane; 842140-40-3
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-(3-Fluoro-4-Methoxyphenyl)-1-Propene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.