Description

2-Bromo-3-(3,5-Difluorophenyl)-1-Propene is a high-value, halogenated organic building block characterized by its reactive alkene and aryl bromide functionalities. This compound is essential for advanced organic synthesis, particularly in the construction of complex molecules for pharmaceutical and agrochemical research. It serves as a critical intermediate for medicinal chemists and process development scientists engaged in cross-coupling reactions, such as Suzuki-Miyaura and Heck reactions, to introduce fluorinated aromatic systems.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the difluorophenyl moiety.
• Material Science: Serves as a monomer or precursor for specialty polymers and advanced materials with unique electronic or surface properties.
• Ligand & Catalyst Development: Employed in the creation of novel phosphine or N-heterocyclic carbene (NHC) ligands for asymmetric catalysis.
• Chemical Biology: Useful as a probe or linker in bioconjugation chemistry and for modifying biomolecules.
• Fluorine Chemistry: A valuable substrate for further fluorination or functionalization studies in organofluorine chemistry.

Basic Information

Product Name	2-Bromo-3-(3,5-Difluorophenyl)-1-Propene
CAS No.	842140-35-6
Molecular Formula	C9H7BrF2
Molecular Weight	233.05 g/mol
Synonyms	1-Propene, 2-bromo-3-(3,5-difluorophenyl)-; 3,5-Difluorobenzeneacryl bromide; (3,5-Difluorophenyl)allyl bromide; 2-Bromo-3-(3,5-difluorophenyl)prop-1-ene; 3-(3,5-Difluorophenyl)-2-bromoprop-1-ene; Allyl bromide, 3,5-difluorophenyl-
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-(3,5-Difluorophenyl)-1-Propene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.