Description

Ethyl 3-[6-Chloro-7-[(3-Chlorophenyl)Methoxy]-4-Methyl-2-Oxochromen-3-Yl]Propanoate is a high-purity, synthetically derived chromene derivative, identified by CAS number 840485-97-4. This compound is of significant commercial interest as a key advanced pharmaceutical intermediate (API intermediate) in the research and development of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex organic molecules for medicinal chemistry applications.

Application

This specialized chromene derivative serves as a critical building block in several advanced chemical synthesis pathways. Its primary and potential applications include:

• Pharmaceutical Intermediate: Serving as a key precursor in the synthesis of potential active pharmaceutical ingredients (APIs) with chromene-based structures.
• Medicinal Chemistry Research: Utilized in drug discovery programs for constructing molecular libraries and exploring structure-activity relationships (SAR).
• Organic Synthesis: Acting as a versatile substrate for further chemical modifications, including hydrolysis, reduction, or coupling reactions to create novel compounds.
• Biochemical Research: Potential use in developing enzyme inhibitors or receptor ligands for biological studies, given its complex heterocyclic architecture.

Basic Information

Product Name	Ethyl 3-[6-Chloro-7-[(3-Chlorophenyl)Methoxy]-4-Methyl-2-Oxochromen-3-Yl]Propanoate
CAS No.	840485-97-4
Molecular Formula	C22H20Cl2O5
Molecular Weight	435.30 g/mol
Synonyms	Ethyl 3-(6-chloro-7-[(3-chlorophenoxy)methyl]-4-methyl-2-oxo-2H-chromen-3-yl)propanoate; 2H-1-Benzopyran-2-one, 3-[2-(ethoxycarbonyl)ethyl]-6-chloro-7-[(3-chlorophenyl)methoxy]-4-methyl-; 840485-97-4; Chromene derivative intermediate; 3-Carbethoxyethyl-6-chloro-7-(3-chlorobenzyloxy)-4-methylcoumarin
EINECS	Contact for details

Quality Control

Our production of this chromene derivative adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, essential for sensitive R&D and synthesis work. Every lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry for verification. Quality management aligns with cGMP principles where applicable, ensuring traceability and documentation for pharmaceutical supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.