Description

2-(3-Fluorophenyl)Ethanethioamide is a specialized fluorinated thioamide building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceuticals and agrochemicals, where the fluorine atom and thioamide moiety impart unique biological activity and metabolic stability. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced bioactivity and environmental persistence.
• Chemical Biology Probe: Serves as a versatile scaffold for creating molecular probes to study enzyme mechanisms and protein-ligand interactions.
• Material Science Precursor: Employed in the synthesis of advanced organic materials, including liquid crystals and polymers with specific electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions for clinical trials.

Basic Information

Product Name	2-(3-Fluorophenyl)Ethanethioamide
CAS No.	834861-71-1
Molecular Formula	C8H8FNS
Molecular Weight	169.22 g/mol
Synonyms	3-Fluorophenethylthioamide; 2-(3-Fluorophenyl)ethanethioamide; 1-(3-Fluorophenyl)-2-thioxoethanamine; 3-Fluorobenzeneethanethioamide; 2-(3-Fluorophenyl)-2-thioacetamide; m-Fluorophenethylthioamide; (3-Fluorophenyl)ethanethioamide; NSC 876841
EINECS	Contact for details

Quality Control

Our 2-(3-Fluorophenyl)Ethanethioamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We adhere to relevant industry standards and can support development under cGMP guidelines for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.