Description

1-(3,4-Dimethyl-Phenyl)-4,4-Difluorobutane-1,3-Dione is a specialized fluorinated diketone compound, serving as a high-value synthetic intermediate in advanced chemical manufacturing. Its molecular structure, featuring a difluorobutane backbone linked to a dimethylphenyl group, makes it a critical precursor for constructing complex molecules with tailored properties. This product is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise building blocks for novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or metabolic diseases.
• Agrochemical Synthesis: Used as a precursor in the development of new-generation herbicides, fungicides, and insecticides, leveraging the fluorine atoms for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating β-diketone ligands used in coordination chemistry and catalysis for asymmetric synthesis.
• Advanced Material Research: Employed in the research of organic electronic materials, such as semiconductors or light-emitting components, due to its conjugated system potential.
• Fluorine Chemistry Research: A valuable compound for academic and industrial research focused on introducing fluorine atoms into complex organic frameworks to modulate physicochemical properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific custom synthesis projects.

Basic Information

Product Name	1-(3,4-Dimethyl-Phenyl)-4,4-Difluorobutane-1,3-Dione
CAS No.	832740-29-1
Molecular Formula	C12H12F2O2
Molecular Weight	226.22 g/mol
Synonyms	4,4-Difluoro-1-(3,4-dimethylphenyl)butane-1,3-dione; 3,4-Dimethylphenyl 4,4-difluoro-3-oxobutanoate; 1-(3,4-Dimethylphenyl)-4,4-difluorobutane-1,3-dione; 4,4-Difluoro-1-(3,4-dimethylphenyl)-1,3-butanedione; DFDB; 3',4'-Dimethyl-4,4-difluorodibenzoylmethane precursor
EINECS	Contact for details

Quality Control

Our 1-(3,4-Dimethyl-Phenyl)-4,4-Difluorobutane-1,3-Dione is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.