Description

5-Iodo-2,3-Dihydropyridazin-3-One is a high-purity iodinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for targeted therapies.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probe Development: Serves as a building block for synthesizing molecular probes to study biological pathways and protein functions.
• Material Science Research: Employed in the synthesis of specialty polymers and organic electronic materials due to its halogenated structure.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) for carbon-carbon bond formation.
• Library Synthesis for High-Throughput Screening: A valuable reagent for generating diverse compound libraries in medicinal chemistry programs.

Basic Information

Product Name	5-Iodo-2,3-Dihydropyridazin-3-One
CAS No.	825633-94-1
Molecular Formula	C₄H₃IN₂O
Molecular Weight	221.98 g/mol
Synonyms	5-Iodo-3H-pyridazin-3-one; 5-Iodo-2,3-dihydro-3-pyridazinone; 5-Iodopyridazin-3(2H)-one; 3H-Pyridazin-3-one, 5-iodo-; 825633-94-1; 5-Iodo-3-pyridazinone; 5-Iodo-1,2-dihydropyridazin-3-one
EINECS	Contact for details

Quality Control

Our 5-Iodo-2,3-Dihydropyridazin-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.