Description

5-Iodo-2-(Phenylmethyl)-3(2H)-Pyridazinone is a specialized iodinated pyridazinone derivative, a high-value intermediate in advanced organic synthesis. This compound matters for its role as a key building block in the development of novel pharmaceutical agents and agrochemicals, enabling precise molecular modifications. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate its unique halogenated heterocyclic structure into target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, or other therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or insecticides, where the pyridazinone scaffold is known for its biological activity.
• Chemical Biology Probe: Serves as a precursor for creating molecular probes to study enzyme function or protein-ligand interactions due to the reactivity of the iodine atom for further functionalization (e.g., cross-coupling reactions).
• Material Science Research: Potential intermediate in the synthesis of organic electronic materials or specialty polymers where halogenated heterocycles are required.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.
• Academic Research: Utilized in university and institutional laboratories for methodological studies in organic synthesis, particularly in metal-catalyzed cross-coupling reactions like Suzuki or Sonogashira couplings.

Basic Information

Product Name	5-Iodo-2-(Phenylmethyl)-3(2H)-Pyridazinone
CAS No.	825633-93-0
Molecular Formula	C₁₁H₉IN₂O
Molecular Weight	312.11 g/mol
Synonyms	5-Iodo-2-benzyl-3(2H)-pyridazinone; 2-Benzyl-5-iodopyridazin-3(2H)-one; 5-Iodo-2-benzylpyridazin-3(2H)-one; 3(2H)-Pyridazinone, 5-iodo-2-(phenylmethyl)-; 825633-93-0; 5-Iodo-2-benzyl-3(2H)-pyridazinone; 2-Benzyl-5-iodo-3(2H)-pyridazinone
EINECS	Contact for details

Quality Control

Our 5-Iodo-2-(Phenylmethyl)-3(2H)-Pyridazinone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled and stored away from direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.