Description

5-Bromo-2-Chloro-4-(Tributylstannyl)Pyridine is a high-purity organotin intermediate of significant importance in advanced organic synthesis. This compound is specifically engineered for use in Stille cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. It is an essential building block for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require precise and reliable coupling partners for the development of novel pyridine-containing molecules.

Application

• Pharmaceutical Intermediate: A key reagent in the Stille coupling synthesis of active pharmaceutical ingredients (APIs), particularly for creating complex heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides that incorporate halogenated pyridine motifs.
• Materials Science Research: Serves as a precursor in the development of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology Probes: Employed in the synthesis of tagged molecules and probes for studying biological systems and drug discovery.
• Catalyst Ligand Preparation: Utilized for the synthesis of specialized pyridine-based ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical and custom synthesis houses serving global R&D needs.

Basic Information

Product Name	5-Bromo-2-Chloro-4-(Tributylstannyl)Pyridine
CAS No.	821773-99-3
Molecular Formula	C17H29BrClNSn
Molecular Weight	487.47 g/mol
Synonyms	4-Tributylstannyl-5-bromo-2-chloropyridine; 2-Chloro-5-bromo-4-(tributylstannyl)pyridine; Tributyl(5-bromo-2-chloro-4-pyridinyl)stannane; 5-Bromo-2-chloro-4-pyridyltributyltin; Stannane, tributyl(5-bromo-2-chloro-4-pyridinyl)-; 5-Br-2-Cl-4-SnBu3-Pyridine
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Chloro-4-(Tributylstannyl)Pyridine is produced and analyzed under strict quality management protocols to ensure consistency and reliability for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques including NMR, HPLC, and GC-MS. Our quality commitment supports compliance with cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This organotin compound is light-sensitive (store away from light) and should be handled under an inert atmosphere (argon/nitrogen) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Tin Content	Contact for details
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.