Description

n-[3,5-Bis(Trifluoromethyl)Phenyl]-N'-[(1R,2R)-2-(Dimethylamino)Cyclohexyl]-Urea is a high-purity, chiral urea derivative of significant interest in advanced pharmaceutical research and development. This compound matters as a sophisticated chemical building block and pharmacological probe, designed for targeting specific biological pathways. It is primarily needed by pharmaceutical companies and contract research organizations (CROs) engaged in the discovery of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral scaffold in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Biochemical Research: Used as a potent and selective ligand or inhibitor in enzymatic and receptor binding assays to study disease mechanisms.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the pharmacokinetic and pharmacodynamic properties of lead compounds.
• Process Chemistry Development: Acts as a reference standard or starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Utilized in universities and institutes for fundamental research in organic synthesis and chemical biology.

Basic Information

Product Name	n-[3,5-Bis(Trifluoromethyl)Phenyl]-N'-[(1R,2R)-2-(Dimethylamino)Cyclohexyl]-Urea
CAS No.	820242-14-6
Molecular Formula	C18H22F6N4O
Molecular Weight	424.39 g/mol
Synonyms	N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(1R,2R)-2-(dimethylamino)cyclohexyl]urea; (1R,2R)-N1-[3,5-Bis(trifluoromethyl)phenyl]-N2-(dimethylamino)cyclohexane-1,2-dicarboxamide (tautomeric form); TRPV1 Antagonist derivative; Chiral Urea derivative; 820242-14-6; UNII-7VJ2805M2F; 7VJ2805M2F
EINECS	Contact for details

Quality Control

Our n-[3,5-Bis(Trifluoromethyl)Phenyl]-N'-[(1R,2R)-2-(Dimethylamino)Cyclohexyl]-Urea is manufactured under strict quality systems to ensure batch-to-batch consistency for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and identity. We adhere to high standards suitable for research and development use, with specifications tailored to meet the rigorous demands of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This material is typically light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥97.0%
Chiral Purity (Chiral HPLC)	≥98.0% de
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.