Description

Potassium 3-(Trifluoromethyl)Phenyltrifluoroborate is a high-purity organotrifluoroborate salt, a crucial building block in modern synthetic chemistry. Its value lies in its exceptional stability and reactivity as a coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient synthesis of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to introduce the versatile 3-(trifluoromethyl)phenyl moiety into target molecules.

Application

• Pharmaceutical Intermediates: A key reagent for constructing drug candidates, particularly those requiring the trifluoromethyl group for enhanced metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the phenyltrifluoroborate group is integral to the active ingredient.
• Material Science Research: Serves as a precursor for creating novel organic electronic materials, liquid crystals, and polymers with tailored properties.
• Cross-Coupling Reactions: Primarily employed in palladium-catalyzed Suzuki-Miyaura couplings to form carbon-carbon bonds under mild conditions.
• Chemical Library Development: Utilized in high-throughput and combinatorial chemistry for the rapid generation of diverse compound libraries for screening.
• Ligand and Catalyst Preparation: Acts as a starting material for synthesizing specialized ligands and organometallic catalysts.

Basic Information

Product Name	Potassium 3-(Trifluoromethyl)Phenyltrifluoroborate
CAS No.	816457-58-6
Molecular Formula	C7H4BF6K
Molecular Weight	251.01 g/mol
Synonyms	Potassium (3-(Trifluoromethyl)phenyl)trifluoroborate; Potassium Trifluoro(3-(trifluoromethyl)phenyl)borate(1-); 3-(Trifluoromethyl)phenyltrifluoroboronic Acid Potassium Salt; [3-(Trifluoromethyl)phenyl]trifluoroborate Potassium Salt; m-Trifluoromethylphenyltrifluoroborate Potassium Salt; Potassium (m-Trifluoromethylphenyl)trifluoroborate; Borate(1-), trifluoro[3-(trifluoromethyl)phenyl]-, potassium (1:1); Potassium 3-Trifluoromethylphenyltrifluoroborate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and manufacturing. Each batch is analyzed to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by NMR or titration), water content (KF), and impurity profiles are available upon request. We adhere to strict in-house quality protocols to guarantee reliable performance in your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (NMR)	≥ 95.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in polar aprotic solvents (e.g., DMF, DMSO)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.