Description

4-(4-Bromophenyl)Tetrahydro-2H-Pyran is a high-purity brominated aromatic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate, enabling the construction of complex molecular architectures through its reactive bromine substituent and stable tetrahydropyran ring. Pharmaceutical, agrochemical, and material science researchers need it for developing new active ingredients and functional molecules. Its defined structure ensures consistent reactivity and purity for critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and transition metal complexes.
• Material Science Research: Building block for synthesizing organic semiconductors, liquid crystals, and advanced polymers with specific electronic or optical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and library production.

Basic Information

Product Name	4-(4-Bromophenyl)Tetrahydro-2H-Pyran
CAS No.	811828-76-9
Molecular Formula	C11H13BrO
Molecular Weight	241.12 g/mol
Synonyms	4-(4-Bromophenyl)oxane; 4-(p-Bromophenyl)tetrahydro-2H-pyran; Tetrahydro-2H-pyran-4-yl(4-bromophenyl)methanone (incorrect but common misnomer); 4-Bromophenyl tetrahydro-2H-pyran-4-yl ketone; 4-(4-Bromobenzyl)tetrahydro-2H-pyran (related isomer); 811828-76-9; Bromophenyl tetrahydropyran derivative
EINECS	Contact for details

Quality Control

Our 4-(4-Bromophenyl)Tetrahydro-2H-Pyran is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and industrial use. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with relevant regulatory frameworks for our customers' target markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.