Description

1,2-Dibromo-3,4-Difluorobenzene is a halogenated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the strategic placement of bromine and fluorine atoms, which serve as versatile handles for further functionalization via cross-coupling and nucleophilic substitution reactions. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those requiring difluorobenzene or dibromobenzene motifs for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the halogen atoms allow for precise structural modifications.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atoms are excellent substrates for Suzuki, Stille, and Buchwald-Hartwig amination reactions to form complex biaryl structures.
• Fluorine Chemistry Studies: An important compound for investigating the effects of adjacent fluorine atoms on reactivity and for synthesizing more complex fluorinated aromatics.
• Chemical Reference Standard: Used in analytical laboratories for method development and calibration in GC-MS or HPLC analysis of halogenated compounds.

Basic Information

Product Name	1,2-Dibromo-3,4-Difluorobenzene
CAS No.	811713-01-6
Molecular Formula	C6H2Br2F2
Molecular Weight	271.89 g/mol
Synonyms	3,4-Difluoro-1,2-dibromobenzene; 1,2-Dibromo-3,4-difluorobenzol; Benzene, 1,2-dibromo-3,4-difluoro-; 3,4-Difluoro-o-dibromobenzene
EINECS	Contact for details

Quality Control

Our 1,2-Dibromo-3,4-Difluorobenzene is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.